الفهرس 
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Abstract
Summary
This present study aimed to measure vitamin D serum level in patients with rheumatoid arthritis and finds its relationship with neuropathic pain.
It was a cross-sectional study conducted in Beni-Suef University Hospital at outpatient and inpatient Rheumatology and Rehabilitation Department. The study included 70 RA patients diagnosis according to the 2010 ACR/EULAR Classification Criteria for Rheumatoid Arthritis
All the seventy individuals included in the study was subjected to a written informed consent for participation in the study, detailed history taking, clinical assessment and Rheumatologic examination through Visual Analogue Scale (VAS), Disease Activity Score (DAS-28), Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) and quality of life assessment by using the modified Health Assessment Questionnaire (m-HAQ). The level of serum vitamin-D level was recorded for all patients in the study.
The collected data were coded then entered and analyzed taking three months using the SPSS version 22.
The study revealed that the gender distribution of studied patients was (78.5%) females and (21.4%) males with significantly higher neuropathic symptoms and signs among females. The majority of our patients were not working (80%). Pain severity in the studied RA patients using the Visual Analogue Scale (VAS), Disease Activity in the studied RA patients using the Disease Activity Score (DAS-28), Neuropathic Symptoms and Signs in the studied RA patiens using the Leeds Assessment of Neuropathic Symptoms and Signs (LANSS) and patients’ quality of life scores measured by (m-HAQ); all had a significantly higher scores among patients with neuropathic pain.
Serum Level of Vitamin D for the studied RA patients; patients with neuropathic pain had significantly lower vitamin D levels as compared with patients without neuropathic pain.
We found a significant negative correlation between serum levels of Vitamin (D) and pain severity in the studied RA patients as assessed by using the Visual Analogue Scale (VAS). Also we found that patients’ (LANSS) scores and Disease Activity Score (DAS-28) were negatively correlated with serum vitamin D levels. In this present study; the serum level of Vitamin (D) was correlated inversely and with the patients’ quality of life scores measured by (m-HAQ).