الفهرس 
-INTRODCTION
-HistoryOnly 14 pages are availabe for public view
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Abstract
P. multocida infection in rabbits is considered one of the most dangerous diseases which affect rabbits all over the world so this study was planned to spotlights on:
o Detection and identification of P. multocida strains that caused different outbreaks to rabbits at New Valley Governorate.
o Detection of sensitivity and resistance of P.multocida to antibacterial agents and different garlic extract concentration.
To establish this goal the following points were undertaken:-
200 sampleswere collected from apparently healthy and diseased rabbits at New Valley Governate the clinical findings and the postmortem findings were recorded and discussed.
Bacteriological investigation of suspected samples regarding cellular, colonial morphology and biochemical characters indicated that the isolates were typical of P. multocida. 79 isolates were identified with the incidence of 39.5%.
Molecular typing of 15 suspected P. multocida isolates by using PCR revealed that all isolates were P.multocida capsular type A with an incidence of isolation 20%.
The challenge strains were sensitive in vitro to Florofenicol(10%) ,doxycyclin(30%),gentamycin(10%),norofloxacin(10%)and(100,75,75,50,25%)garlic ;extract. Challenge strains were resistant in vitro to amoxicillin (25%), clositine sulphate (10%), 12.5% garlic extract.
In our study Florofenicol 10% and garlic extract100% are recommended for treatment and prevention of rabbit pasteurellosis.
In our study, testing therapeutic efficacy of Florofenicol 10% and 100% garlic extract was carried out in vivo.It is worth to mention that Florofenicol 10%, 100%aquas garlic extract in drinking water was observed for prevention and treatment of P.multocida infection in rabbits.
It is naked that 100% garlic extract, beside its antibacterial activity against P.multocidain rabbits has a positive effect on growth performance of rabbits.
7-Conclusions
It could be concluded from the present study that eradication of the Pasteurella organisms is difficult because they occur as commensal in nasopharynx and digestive tract. of rabbits, anti-bacterial treatment is the primary choice of disease control.
Our study illustrates that the range of eligible antimicrobial agents against P.multocida is still wide. The use of Florofenicol 10%to be the most active antimicrobial agents has protective and therapeuticeffects on rabbits against P. multocida infection.
In our study we found that 100% aquas garlic extract has protective and therapeuticeffects on rabbits against P. multocida infection.
Our advice to rabbit breeder that several management strategies have been proven to successfully reduce pressure in rabbit production. The primary way of reducing risk of rabbit pasteurellosis is “all-in all-out” management, as it allows thorough cleaning and disinfection. A second tool is the alternatives use of antibiotics (Florofenicol 10%)in drinking water are useful in the absence of good management such a consistent approach, both preventive and curative use of antibiotics remains the easiest and most inexpensive way to control pasteurellosis in rabbit production.
Finally, Effectiveness of 100% garlic extract in drinking water and some other herbs plant have shown some potential in reducing rabbit’s pasteurellosis problems and had positive effect on growth performance of rabbits