الفهرس 
Alzheimer’s diseaseOnly 14 pages are availabe for public view
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Abstract
Alzheimer’s disease (AD), also referred to simply asAlzheimer’s, is a chronic neurodegenerative disease that usually starts slowly and worsens over time. It is the cause of 60% to 70% of cases of dementia. The most common early symptom is difficulty in remembering recent events (short-term memory loss). As the disease advances,symptoms can include problems with language, disorientation(including easily getting lost), mood swings, loss of motivation, not managing self care, and behavioural issues. As a person’s condition declines, they often withdraw from family and society. Gradually, bodily functions are lost, ultimately leading to death. Although the speed of progression can vary, the average life expectancy following diagnosis is three to nine years. The aim of our study is to investigate methods for early detection of alzheimer disease in the preclinical state and to determine whether behavioural symptoms like depression, anxiety or sleep disturbances in non demented participants were associated with changes in FDDP-PET binding values so they can be a predictor of alzheimer disease. In our study, all the subjects were 50 they have clinical presentation in the form of lack of concentration and memory affection. In our study, we use PET brain for early detection of alzheimer by using FDG, also we do Magnetic resonance imaging. We use different scales for detection of association of depression, anxiety, sleep problems with alzheimer. There was clinical correlation between depression and Alzheimer patients also there was clinical correlation between anxiety symptoms and early detecetion of alzheimer. All of that was done by using scales for both depression and anxiety in the form of geriatric depression scale and state trait anxiety inventory. All of the subjects have depressive symptoms and anxiety symptoms which ensure strong relatinship between anxiety, depression with alzheimer disease.
Also all the subjects have sleep problems which detect strong relationship between sleep problems and alzheimer‘s.