Search In this Thesis
   Search In this Thesis  
العنوان
A Comparative Study of Residual Volume in Donors for Living Donor Liver Transplantation
الناشر
faculty of medicine
المؤلف
Asaad,Dr. Nourhan Muhammad Diaa El Din
هيئة الاعداد
باحث / نورهان محمد ضياء الدين أسعد
مشرف / الأستاذ الدكتور/ حسن زكريا شاكر
مشرف / الأستاذ الدكتور/ هاني سعيد عبد الباسط
مشرف / الدكتور/ محمد عبد الستار عبد الحميد
الموضوع
Living Donor Liver Transplantation Liver Transplantation Residual Volume in Donors
تاريخ النشر
2019
عدد الصفحات
131 P.
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
جراحة
تاريخ الإجازة
1/1/2019
مكان الإجازة
جامعة عين شمس - كلية الطب - الجراحة العامة
الفهرس
Only 14 pages are availabe for public view

from 131

from 131

Abstract

Introduction: Living donor liver transplantation (LDLT) was introduced in 1989 to overcome the severe shortage of size-matched DD organs for pediatric recipients. Given the increasing shortage of DD grafts for adults in North America and Europe, living donation (LD) was now being explored as a potential solution to the shortage of DD organs for adults also. Aim: This study aims at the exploration of this last point. Whether or not minimizing the residual volume in donors after LDLT affects donors’ morbidity. Concentration will be on postoperative donors’ bilirubin level, liver transaminases pattern and complications according to Clavien’s scale. Patients and Methods: It is a Comparative Retrospective Observational Cohort study included 44 liver donors operated upon in Ain Shams Specialized Hospital Liver Transplantation Unit and in Egypt Air Liver Transplantation Unit from January 2014 to April 2017. Results: There was no significant difference between two groups regards age, gender, fibrosis, steatosis, operation center, postoperative bilirubin (After how many days it returned to normal, maximum and mean postoperative bilirubin), postoperative complications (didn’t pass grade 2 in group A and grade 3 in group B), liver enzymes (postoperative AST and ALT) and Hospital stay, There were no difference between the two groups in the follow up except for elevation of liver enzymes that didn’t return to normal for more than 15 days in donor 9 and elevation of bilirubin in donors 3, 4 and 10 in group (A) and in donors 13, 24, 25, 26, 32, 33 and 43 in group (B). Conclusion: It is concluded that donors with low RVs ”not less than 33%” could be chosen and operated upon with no significant complications postoperatively that could affect donors’ safety, We suggest that regular follow up of donors is recommended for 5 years. Also more research regarding RV, donors’ safety, selection and complications is recommended as Egypt is the first country in liver disease worldwide.