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العنوان
The Utility of Fibrinogen/C-reactive protein Ratio versus D-dimer and Fibrin Degradation Product in Diagnosis of Overt Disseminated Intravascular Coagulation in Intensive Care Unit patients/
المؤلف
Nawar,Nancy Raouf Wagid
هيئة الاعداد
باحث / نانسي رؤوف وجيد نوار
مشرف / شريف وديع ناشد
مشرف / أحمد على الشبينى
مشرف / محمد محمود معروف
تاريخ النشر
2018
عدد الصفحات
143.p:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
العناية المركزة والطب العناية المركزة
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة عين شمس - كلية الطب - Anesthesiology
الفهرس
Only 14 pages are availabe for public view

from 143

from 143

Abstract

Background: Coagulopathies in ICU are one of the most common complications in ICU. DIC is one of the most threating coagulopathies in ICU. Early diagnosis of DIC is very important for early intervention for better prognosis. DIC is caused by several pathologies like sepsis, trauma, obstetric causes and malignancies.
Aim of Work: to compare between thee sensitivity between fibrinogen/CRP ratio and FDPs and D-Dimer.
Patients and methods: After obtaining approval from the medical ethical committee at Ain Shams University, this observational prospective study was conducted at Ain Shams University Intensive care units. The study included 70 patients in Demerdash ICU after including patients with ISTH score ≥5.Two samples were collected from each patient
Results: The results were in favor to the classical parameters of diagnosis of overt DIC in comparison with the new parameter of DIC. It showed that D-dimer and FDPs together were more sensitive than fibrinogen/CRP ratio.
Conclusion: The D-dimer and FDPs tests offered the best panel in the diagnosis of DIC especially in overt DIC due to their high sensitivity.