الفهرس 
Platelet-Rich Plasma & Growth FactorsOnly 14 pages are availabe for public view
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Abstract
C
hronic wounds cause patients severe emotional and physical stress as well as creating a significant financial burden on patients and the whole healthcare system.
The vast majority of chronic wounds can be classified into three categories: venous ulcers, diabetic, and pressure neuropathic ulcers.
The normal wound healing process is dynamic and complex having three phases: inflammation, tissue formation and tissue remodeling, however if the normal healing process is interrupted, an ulcer can become chronic in nature due to lack of growth factors and cytokines which delay the healing process
The use of Platelet-Rich Plasma (PRP) in medicine has become increasingly more widespread during the last decade. Its use is based on the fact that platelets contain many growth factors in their alpha granules. These factors have a well-known role in the process of tissue repair, These factors are critical in the regulation and stimulation of the wound healing process, and they play an important role in regulating cellular processes.
The purpose of this prospective clinical pilot study was to evaluate the safety and efficacy of lyophilized human platelets growth factors (L-GF) as a novel technology for processing and preparation of human platelets in treating chronic cutaneous wounds (non healing ulcers).