الفهرس | Only 14 pages are availabe for public view |
Abstract This study was one of the first studies that correlated between amyloid A and different demographic data in preeclamptic women. In currant study among cases group, we found non-significant correlation between Amyloid A and age (r = 0.05 & p=0.66) and there was non-significant correlation between Amyloid A and BMI (r= -0.001 & p=0. 66), hemoglobin concentration (r= - 0.08 & p=0. 47) or platelet count (r= - 0.17 & p=0. 12). Overall, statistically significant positive correlation was found between serum amyloid A level and most of the indices of severity of preeclampsia. A statistically significant correlation was found between serum amyloid A and systolic blood pressure measurements (r = 0.82 & p < 0.001) and diastolic blood pressure measurements (r = 0.82 & p < 0.001), ALT (r = 0.64 & p < 0.001), AST (r = 0.45 & p < 0.001) serum creatinine (r = 0.26 & p =0.02) and albuminuria (r = 0.73 & p < 0.001) and we think that this is a matter of association rather than causation Our data sustain the limited number of studies investigating the SAA levels in both preeclamptic and healthy pregnant women, in which it was hard to reach a consensus regarding the association between SAA levels and preeclampsia. Taken in consideration that an elevated plasma level of SAA in preeclamptic women should be considered pathologic, we believe that the response of relationship between the preeclampsia and SAA levels could be caused by an inflammatory condition associated with preeclampsia. |