الفهرس 
Components of the immune systemOnly 14 pages are availabe for public view
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Abstract
The research effort to understand the immunological response to a semi-allogeneic pregnancy extended over more than a half century, the recent studies support the concept that a modulated but dynamic, responsive and definitely not a suppressive immune system, is vital for a successful pregnancy. Importantly, this finding helps to understand the source of many pregnancy disorders that lead to destructive consequences for children and their families.
The immune response during pregnancy acts as a complex quality control system and knowing how this relates to infertility and miscarriage occurrence needs to be investigated.
Definitely, researches can emerge a solution for preeclampsia once understanding how NK cells, Treg cells, dendritic cells, and macrophages all interact to control placental vascular development in the early stage of placental development.
Programing the sequence of events that lead to activated leukocytes, to be enrolled into gestational tissues, and initiate parturition at the end of gestation is a major challenge that gives new hope for understanding preterm labor and finds options for its prevention.
Moreover, the natural immunological situation of pregnancy contains an excellent model for exploring how tumors usurp immune rejection and for founding new plans that improve transplantation of organs and cells. Traditional therapies have focused on the host, with administration of cytotoxic drugs to the tumor-bearing patient, and modulation of host immune responses in graft recipients. So far pregnancy immunology has taught experimentalists and clinicians that both the host and the invading tissue cooperate to develop a protected environment. Now, therapies are being created wherein host immune cells attacking tumors are reconstructed to overcome the tumor elusive strategies, and gene-modulated organ and tissue grafts are being built to similar host tolerance in pregnancy.
Furthermore, the demonstration that a clinically silent viral infection can markedly change the immune-modulated and receptive maternal-fetal interface emphasizes the need for better detection, treatment and prevention of these viral infections. This will not only lead to better pregnancy outcomes but can also positively affect postnatal development, as viral infections and the following inflammation have been involved in the mental health problems and in the immune diseases such as allergies and asthma. With the evolution of new diseases developed secondary to viral infection and the persistent risk of pandemics, understanding the complexity of the immune response during pregnancy is pivotal for the evolution of convenient tools and approaches to protect the mother and the fetus.