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Abstract Acute toxicity is globally considered as a major health problem affecting different populations especially in developing societies , with increasing danger of elderly poisoning all over the world. Worldwide, the fraction of individuals aged more than 60 years increased from 9.2% in 1990 to 11.7% in 2013 and expected to reach 21.1% by 2050. In all Arab countries, Egypt has the largest number of older adults, where, nearly 4.6 million adults are more than 60 years old and almost 320,000 Egyptians are 80 years old and older. Aging is considered as a process that results in physiological decline in all body systems, and increased incidence of age-related degenerative diseases. In addition, the increased prevalence of multiple comorbidities in elderly is usually associated with increased risks of polymedication. Therefore, elderly are considered at great risk for toxicity. Moreover, the clinical profile of acute poisoning in the elderly is expected to be different from younger adults. Hence, the aim of this work was to reveal the pattern and outcome of acute poisoning in elderly patients, and to detect possible risk and prognostic factors affecting the outcome in acutely poisoned elderly. This study was a cross sectional study conducted on elderly patients admitted to Toxicology Unite, Tanta Emergency University Hospital throughout the period from 1st of July 2016 to the 31th of December 2017 (prospective part), with collection of patients’ data (retrospective part), from the 1st of January 2013 till the end of June 2016. All cases aged more than 60 years admitted to with acute poisoning throughout the five years period from the 1st of January 2013 to the 31th of December 2017 were included, with exclusion of patients with chronic poisoning. |