الفهرس 
Stromal Wound Healing Following PRKOnly 14 pages are availabe for public view
 |  | from | 82 |  |  |
| | | from | 82 | | |
Abstract
Corneal endothelium is considered the corner stone to maintain corneal clarity via hexagonal cells which are responsible for maintaining the hydration of the stroma by actively removing the water with active pump system. In childhood the endothelial count is about 4000 cells/mm2 and this count subsides with aging process reaching about 2500 cells/mm2 in the 8th decade, the minimum cell count that can maintain proper action of endothelium is about 400-700cells/mm2. Corneal refractive surgery widespread especially photo-refractive keratectomy with adjuvant mitomycin-c was very challenging to observe any changes that may disrupt endothelial action whether from ablation or from topical application of mitomycin-c. Our study was conducted on 60 eyes of 30 patients scheduled for photo-refractive keratectomy in low to moderate myopia. The patients are randomly divided into two groups group A are assigned to undergo PRK with intraoperative topical application of mitomycin-c, the patients of group B assigned to undergo to PRK without adjuvant instillation of mitomycin-c. The present study reveals no significant change in the cell density or morphology and function of endothelium in both groups 3 month after surgery compared to pre-operative data.