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Abstract SUMMARY AND CONCLUSION This study was performed to evaluate carotid media thickness measurement as a marker of premature atherosclerosis in systemic lupus erythematosus (SLE) patients with and without nephritis. This study involved 30 patients with SLE without nephritis (GI) (females 26 (86.7%) and males 4 (13.3%)) with mean age of 28.60 ± 588 years and with mean disease duration of (4.95±3.61) years. Also involved 30 patients with SLE with nephritis (GII) (females 25 (83.3%) and males 5 (16.7%) with mean age of 29.67 ± 6.16 years and with mean disease duration of 7.20 ± 3.53 years in addition to 30 healthy volunteers (GIII) (21 females and 9 males with mean age (28.53 ± 5.35 years) as control group. Patients are diagnosed as SLE according to the American College of Rheumatology (ACR) criteria or Systemic lupus International Collaborating Clinics (SLICC) 2012 criteria. All patients were subjected to the following: Complete history taking. Full clinical examination. Laboratory investigation. Doppler examination of the extra-cranial portion of the carotid arteries to measure the intima-media thickness (IMT). The results showed the following: There was significant difference between GI&GII (p1:0.048) regarding intima media thickness. |