الفهرس 
Acne ValgarisOnly 14 pages are availabe for public view
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Abstract
Acne vulgaris (AV) is a chronic inflammatory skin
condition. Increase in sebum production, abnormal keratinization of the
pilosebaceous follicle, Propionibacterium acnes (P.acnes) and an
inflammatory immune response all are implicated in its etiology. Human
beta defensin-3 (HβD3) is an antimicrobial peptide (AMP) expressed in
the epidermis from the epidermal keratinocytes. HβD3 exhibited a strong
antimicrobial activity against P.acnes and strengthened the skin’s physical
barrier function, a decline of which gives leads to hyperproliferation and
hyperkeratinizaon of epidermal keratinocytes, pathogenic factors in acne.