Search In this Thesis
   Search In this Thesis  
العنوان
THE ROLE OF DIFFUSION- MRI IN charACTERIZATION OF HEAD AND NECK MASSES /
المؤلف
Moustafa, Sara Aly Roby.
هيئة الاعداد
باحث / سارة علي روبي مصطفي
مشرف / محمد عبد اللطيف محمود
مشرف / نادر شعبان زكي
مشرف / .انجي شوقي الكيال
الموضوع
Head and neck masses. diffusion.
تاريخ النشر
2019.
عدد الصفحات
132 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
20/1/2019
مكان الإجازة
جامعة الفيوم - كلية الطب - الأشعة التشخيصية
الفهرس
Only 14 pages are availabe for public view

from 145

from 145

Abstract

Diagnosis of head and neck lesions is difficult due to the compli¬cated anatomic structure and different histological components of the many tissues that the neck contains,.Diffusion weighted imaging (DWI) is now part of most oncologic magnetic resonance imaging (MRI) protocols and is commonly used in routine examinations for tumor characterization and staging and for detection of residual disease after chemo-radiotherapy
Methods : fifty patients, 32 males (64%) and 18 females (36%) .All cases had been subjected to : Clinical assessment sheet by the referral doctor.Revision of the radiological investigations previously done for the patients and an MRI study with routine axial T 1 and T 2 weighted images and in addition a protocol of Diffusion weighted images was applied in three orthogonal directions and ADC map was generated.
Results: the mean ADC value of benign masses was higher than that of malignant masses .These differences in ADC values may be explained by the differences in the histopathological characteristics of benign and malignant tumors. The mean ADC for that of benign lesions was 1.99 x10-3 and the mean ADC for that of malignant lesions was 0.99 x 10-3 with significant difference between values of ADC for benign and malignant lesions . We used a ROC curve to determine a cutoff point of 1.45 x10-3 or less with 100 %sensitivity and 90.7 % specificity the area under the curve is about 0.982.
Conclusion: The use of diffusion weighted image and ADC may be used to help in characterization of head and neck lesions .DWI has a high sensitivity and specificity , and maybe a reliable, non-invasive imaging modality for the differentiation of head and neck masses and their nature
Key words: Head and neck masses , DWI, diffusion
weighted imaging ,ROC and ADC