الفهرس | Only 14 pages are availabe for public view |
Abstract SUMMARY The study was done to evaluate the accuracy of integrated positron emission tomography and computed tomography (PET/CT) using 18Ffluorodeoxyglucose (FDG), for follow-up of patients with suspected recurrent breast cancer. Approximately 1 in 10 women will suffer from breast cancer during their lifetime. Among malignancies, breast cancer is the second cause of death in women after lung cancer. Early detection is the most effective strategy for reducing mortality from breast cancer. Mammography is the only screening method that has been shown to affect patient survival. The study was conducted on 30 female patients with past history of breast cancer .The patient’s ages were between 31-75 years old, who had whole-body 18F- FDG PET/CT. Our study suggests that; 1) PET/CT is an accurate, sensitive and reliable modality for screening and detection of breast cancer recurrence. 2) PET/CT appears to be an effective surveillance tool, as it is able to cover the whole body in a single procedure and shows good performance. 3) True FDG uptake is underestimated in small cancer deposits because of the limited spatial resolution of current PET devices. 4) FDG/PET has been shown to be of limited rule in detecting osteoblastic bone metastases due to hypometabolic activity of the lesions. 5) FDG PET/CT is likely to be more useful as a screening test for distant metastases in patients with an advanced stage of breast cancer than in those with an early stage. |