الفهرس 
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Abstract
Alteration in serum concentrations of several trace elements have been reported to occur in type 1 diabetes mellitus. These trace elements are suspected to have a role in the pathogenesis and progression of the disease.
Our aim in this study was to measure the serum levels of selenium, copper and zinc in children with type 1 diabetes mellitus and compare them with that of apparently healthy children and to correlate their levels with glycated hemoglobin (HbA1c).
This study included 100 children classified into two groups: diabetic children group (6o children) and healthy control group (40 children).
All children included in the study were subjected to; history taking, complete clinical examination, as well as laboratory investigations including (fasting blood glucose, HbA1c, serum selenium, copper and zinc levels).
The Se and Zn levels of children with TIDM were significantly lower than those of controls and lower in uncontrolled diabetic children than in the controlled diabetic children, regardless of the duration after diagnoses. Glycated hemoglobin (HbA1c) levels were found to be negative correlated with Se and Zn levels.
On the other hand, Cu levels of children with TIDM were significantly higher than those of controls and higher in uncontrolled diabetic children than in the controlled diabetic children and there was significant positive correlation between glycated hemoglobin (HbA1c) with Cu levels.