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Abstract Movement disorders are very common, especially in the elderly population. They include a variety of neurological conditions that are generally caused by dysfunction in a region of the brain called the basal ganglia. Movement disorders, such as Parkinson disease (PD), tremor, tics and dystonia, are common conditions. The overall prevalence of PD, for example, is 1% in people aged 65–85 years, increasing to 4.3% above the age of 85 years. The prevalence of essential tremor the most common form of tremor is 4% in people aged over 40 years, increasing to 14% in people over 65 years of age. The prevalence of tics in school-age children and adolescents can be as high as 21%. The aim of our study is to investigate the clinical profile of patients with different movement disorders presented to Ain Shams university outpatient clinics for comprehensive epidemiological survey. It is cross sectional descriptive prospective study that evaluated 158 patients with variable presentations of movement disorders who attended to our patient clinics among the last eight months. We hypothesized that, Parkinson’s disease is the most frequent presentation in the clinic followed by dystonia patients, patients with chorea, then patients with tremor and tics.Both the incidence and prevalence of Parkinson disease increase with age, and the prevalence may be as high as 1 in 50 for patients over the age of 80 years. There was equal distribution among both sex, (57.58%) of patients were from rural area. Moreover there is significant delayed diagnosis of involuntary movement disorders in rural areas. Regarding tremor, the ET is more common in males with 26% of subjects had positive FH. There is significant relation between duration of ET and its severity |