الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 190 |  |  |
| | | from | 190 | | |
Abstract
Summary and Conclusion
Cirrhotic livers are characterized by advanced fibrosis and
formation of hepatocellular nodules which are classified histologically as
either regenerative nodules, dysplastic nodules, or neoplastic lesions.
However, their accurate characterization may be difficult even at
histopathological analysis. Differential diagnosis may be facilitated by
comparing the clinical and pathological findings with radiological
imaging features.
MR imaging is more useful than computed tomography and US in
diagnosing the premalignant cirrhotic nodules from the malignant ones
as it is the main issue for early detection and management of HCC. MRI
provides better soft-tissue contrast and identification of different tissue
properties by their signal appearance on different MR phases while in
MSCT we judge only on dynamic post contrast study. Moreover, a wide
variety of contrast agents are currently available for use in MR imaging.
For hepatic focal lesions detection and characterization,
conventional MRI relies on T1-weighted, T2-weighted and dynamic
gadolinium-enhanced T1-weighted imaging.Additionally, DW MRI in
the liver is a relatively new and increasingly used imaging technique. It
has the advantage that it can be obtained during a single breath-hold,
there is no need to use contrast media, and it provides unique
information that reflects tissue cellularity and organization. The ADC
maps can also provide quantitative measurements of tissue water
diffusivity which can be used not only for disease assessment, but also
for the evaluation of disease response to treatment.