الفهرس | Only 14 pages are availabe for public view |
Abstract Summary Erectile dysfunction is defined as permanent inability to achieve or maintain an erection sufficient for satisfactory sexual intercourse for a period of at least 6 months. Diabetes has been associated with corpus cavernosum smooth muscle changes, such as increased connective tissue synthesis and atrophy of smooth muscle within the corpus cavernosum bodies in humans and animal models. These structural changes are correlated with an increased incidence of veno-occlusive dysfunction and erectile failure consistent with peripheral vascular disease seen in diabetes. Diabetes is associated with intimal, medial, and luminal changes within the artery leading to atherosclerosis. Atherosclerosis is a multifocal, smouldering, immune-inflammatory disease affecting mainly medium and large sized arteries. There is growing evidence that, in addition to traditional risk factors, vascular wall inflammation, adverse clinical vascular events play a key role in pathogenesis of vascular disease and atherosclerotic process. Accordingly, this study aimed to assess the association between diabetes and changes in the penile doppler ultrasonography in patients with erectile dysfunction. Also, the influence of factors like control of diabetes, duration of diabetes and presence of diabetic related complications on Doppler parameters. We used ultrasonographic parameters to evaluate the link between duration, control of diabetes on the cavernosal arteries by determining PSV, EDV, RI, internal diameter, IMT and AWMI of cavernosal arteries. In order to accomplish this aim, the assess the association between diabetes and changes in the penile doppler ultrasonography in patients with erectile dysfunction. The. |