الفهرس | Only 14 pages are availabe for public view |
Abstract IE is a very complex disease with a serious prognosis. Despite improved preventive strategies and rational antibiotic prescribing, the incidence of IE has not decreased in the last three decades. In contemporary population-based studies of IE in industrialized countries, in-hospital mortality ranges from 15 to 22%, and 5-year mortality is approximately 40%. This lack of improvement in prognosis might be due to the fact that IE is now occurring in old people, in patients unaware of having a cardiac disease, in patients with prosthetic valves, and is being caused by aggressive organisms such as Staphylococci. Surgery for IE has been potentially lifesaving and is indicated in approximately 50% of patients. Operating during inactive (healed) phase of the disease process, in a sterile field, is highly desirable. If medical treatment fails to eradicate the infection, however, or in conditions such as cardiac failure, severe valvular dysfunction, embolism, abscess formation, demonstration of large mobile vegetations on echocardiography, fungal infection, or early PVE, expeditious operation, in the face of an ongoing infection, may be warranted. Early identification of patients who are at high risk of death or complications of IE may offer the opportunity to improve the outcome of this disease. Several studies have demonstrated that among the complications of IE, congestive heart failure has the greatest impact on prognosis. The aim of this study was to evaluate the risk factors affecting the early outcomes of surgical treatment of infective endocarditis. |