الفهرس 
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Abstract
Summary
This study was conducted in Chest departments ,in Kasr Al Ainy and in Beni suef university hospitals in the period from January 2017 to January 2018. It included thirty patient admitted with undiagnosed exudative pleural effusion, after being evaluated by thoracothentesis
Aim of the study was Comparison of parietal pleural biopsiestaken by rigid forceps and those taken by cryoprobe during medical thoracoscopy in cases with un- diagnosed pleural effusion regarding Surface area , depth, diagnostic yield and tissue viability.
All our patients were subjected to:
Complete history taking, Clinical examination, CBC, serum albumin ,creatinine.PT, PC and INR ,Analysis of pleural fluid regarding glucose, LDH, Protein and cytology, ADA, Culture ,sensitivity when needed, Tuberculin skin test in some cases , Chest X-ray, CT Chest , Medical Thoracoscopy and pleural biopsies were taken by rigid Forceps and cryo probe in the same setting.
Among the studied patients, it was found that:
Higher incidence of Malignancy in Males compared to Female
Mesothelioma is the most frequent diagnosis
Malignancy is common among smokers
Mean surface area of rigid forceps biopsies was (0.8 cm2 ) larger than mean surface area of cryo probe biopsies (0.3cm2).
Cryo probe biopsies were more deeper than rigid forceps biopsies
Cryo probe biopsies as regarding tissue viability was better than rigid forceps biopsies
Cryo technique has the same diagnostic yield as that of rigid forceps.
This procedure is generally safe with no complications have been reported regarding bleading and pain.