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العنوان
Cardiac MRI: Dobutamine stress myocardial Perfusion Using 3T MRI /
المؤلف
Mabrouk,Alaa Mahmoud Abdellatif.
هيئة الاعداد
باحث / Alaa Mahmoud Abdellatif Mabrouk
مشرف / Maha Khaled Hassanein Abdelghaffar
مشرف / Amal Ibrahim Ahmed Othman
تاريخ النشر
2018
عدد الصفحات
157p.:
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة عين شمس - كلية الطب - الأشعة التشخيصية
الفهرس
Only 14 pages are availabe for public view

from 157

from 157

Abstract

Cardiovascular disease is important one of the leading cause of death in the United States. Each year, over 1.5 million U.S. residents have myocardial infarctions, roughly one-third of whom die. Although there has been a dramatic reduction in the death rate due to cardiovascular disease over the past 30 years, it still accounts for 22% of all deaths (Thom et al., 2006)
Diagnostic imaging has played an important role in the proper assessment and management of coronary artery disease. Advances in rapid magnetic resonance (MR) imaging technology and its application to cardiac imaging have shown that MR imaging has tremendous potential for evaluation of coronary artery disease and cardiac disease in general (Yun et al., 2015)
The popular used techniques include stress single-photon emission computed tomography (SPECT), stress echocardiography and stress Cardiac Magnetic Resonance (CMR) account for the vast majority of tests currently performed for ischemia detection. Stress CMR is currently accepted as a noninvasive gold standard technique for the assessment of cardiac structure, ventricle mass and function. No doubt that MRI has a higher spatial resolution compared to echocardiography, MR is non ionizing i.e. no radiation side effects as cardiac catheterization and offers the viability assessment with the use of contrast imaging,assessment of all cardiac valves and extra-cardiac structures.
The aim of our study is to assess the role of cardiac MRI stress perfusion in demonstrating the myocardial viability for evaluation of patients suspected or already established known with CAD and LV dysfunction.
This study included 20 patients, ranging in age from 42 to 70 year old. They were referred to the Radiology center during the period from 2017 to 2018, those patients were examined by MRI.
In our study, cardiac MRI stress perfusion clinically validated first line technique to assess global and regional LV function as well as myocardial viability and showed more effectiveness through testing the diastolic function which can be integrated in a single comprehensive cardiac examination combining the LV systolic& diastolic function tests with localization and quantification of the extent of ischemic myocardial tissue and detected perfusion defects.
Stress cardiac magnetic resonance (CMR) provides a high negative predictive value for adverse cardiac events in subjects with known or suspected coronary artery disease (CDA). CMR has already proven additional value, in some cases providing accuracy and reproducibility superior to echocardiography in detection of ischemic cascade in myocardium.