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العنوان
Retrospective analysis of treatment modalities and survival of patients with cervical cancer
in Ain Shams University Maternity Hospital
from 2012 to 2017 /
المؤلف
Helal, Mostafa Mohamed Othman.
هيئة الاعداد
باحث / مصطفى محمد عثمان هلال
مشرف / عمرو حسن الشلقانى
مشرف / أحمد محمد ممدوح
تاريخ النشر
2018.
عدد الصفحات
143 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض النساء والتوليد
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة عين شمس - كلية الطب - Obstetrics & Gynecology
الفهرس
Only 14 pages are availabe for public view

from 132

from 132

Abstract

Cervical carcinoma is the second most common cause of gynecological malignancy death following ovarian carcinoma.
Cervical cancer is considered a preventable disease and it has a detectable precursor status which is treatable. So well established screening program can lead to decline in the incidence of mortality and morbidity.
The aim of this work was to study the size of the problem of cervical cancer in Egypt. Our study population was the patients presented to Ain Shams University Maternity Hospital from 2012 to 2017, diagnosed as cervical cancer.
The data includes 147 women who are diagnosed as having cervical cancer from 1-1-2012 to 31-12-2017 as retrospective analytical study. We collect name, age, parity stages, Histopathology, treatment, morbidity and survival about each woman and analyze this data.
The results of our study showed that the mean age 52.3 years, standard deviation 10.8 which means that we have to continue screening even after the age of 60 years.
Most of cases were illiterate 91.8% which may contribute to the non adherence to screening and management.
Most of the cases diagnosed at late stages (41.5% stage IIIB and 38.8% stage IIB) and hence the importance of well-established screening program.
In the current research study survival was statistically significantly higher in early stages. (81.8 % of the cases survived in stage I and 33.3 in stage IV).
The most frequent treatment modality was primary radiotherapy without surgery (53.2% with 60% survival) Then primary radiotherapy with surgery (22.5 % with 56.2 % survival) and the last was 1ry surgery only (21.6 % with 80% survival).The most common treatment modality is 1ry radiotherapy because most of the patients presented in late stages and the highest survival in 1ry surgery because it takes place in early stages. Completion and salvage surgery can be used in patients who are in need for brachytherapy when brachytherapy is not accessible. There is no statically significant difference between occurrence of Complications with treatment modalities except for Lymphedema and blood transfusion requirement that were significantly least frequent in Primary radiotherapy without surgery.
Screening programs should be made widely and sexual intercourse should be restricted on marriage only which agrees with our religion and habits and most effective method in prevention of cervical cancer. Vaccination of women at risk (women with multiple sexual partners, low immune) should be started in Egypt.