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العنوان
Role of Diffusion Weighted MRI in Grading of Endometrial Carcinoma \
المؤلف
Gaber, Nourhan Abd Elmohsen.
هيئة الاعداد
باحث / نورهان عبد المحسن جابر
مشرف / لبنى عبد المنعم حبيب
مشرف / رشا صلاح الدين حسين
مناقش / لبنى عبد المنعم حبيب
تاريخ النشر
2018.
عدد الصفحات
127 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة عين شمس - كلية الطب - الأشعة التشخيصية
الفهرس
Only 14 pages are availabe for public view

from 127

from 127

Abstract

Although TVUS is the first imaging modality that can be used for detection of uterine mass lesion and the final diagnosis of the endometrial carcinoma is based on the histological examination; it is important to have preoperative road map to decide whether surgery is required, and which type of surgery is appropriate.
Thus, MRI can help avoiding unnecessary surgery. It tells us the exact volume, shape, and direction of the primary lesion, local extent of the disease, and nodal status accurately, which helps the clinician in treatment planning.
MRI is an ideal non-invasive technique and superior to other imaging modalities in the evaluation of pelvic abnormalities. The anatomical relation of the visceral organs, the differential zonal anatomy of the corpus uteri and the cyclical endometrial changes during the menstrual cycle are well depicted with MRI.
In addition, lesion characterization is done with the help of functional MRI. Complementary role of both conventional and functional MRI is necessary in morphological and functional characterization of the lesion.
MRI has been found to be cost-effective because in addition to its capability of accurate staging, it can replace multiple other radiological and interventional procedures, as computed tomography (CT), cystoscopy, and sigmoidoscopy.
Mean ADC value measurement can provide useful information in differentiation benign from malignant endometrial lesions. This information could be clinically relevant in those patients where preoperative endometrial sampling is not possible.
It helps to decide operability, the type of operation and aids in the selection of patients who need a special referral to a gynecologist oncologist.
The sensitivity, specificity and accuracy of ADC value in grading of endometrial carcinoma in relation to histopathology 90.6%, 87.5% and 90.0% respectively.
DW-MRI has higher sensitivity and accuracy in staging of endometrial carcinoma than DCE-MRI. So,it could replace DCE-MRI especialy if there is contraindication or non availability of contrast material.