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Abstract Summary and Conclusion Extracranial carotid stenosis is a major cause of stroke. It has been estimated that carotid artery disease is responsible for 20% to 30% of stroke. The 3-year risk of ipsilateral ischemic stroke is 16.8% for patients with severe (70-99%>) stenosis in patients treated medically. The well-established indications of CAS as a first therapeutic option for a carotid revascularization are the following: recurrent stenosis after CEA, radiation-induced carotid stenosis, anatomical features (high carotid bifurcation near the skull base), tandem lesions (proximal common carotid artery stenosis or distal stenosis in the carotid siphon associated with the carotid bifurcation stenosis). Compared with CEA, CAS has the advantage that it can be done with the patient under mild sedation, requires no incision and thus avoids the risk of cranial nerve palsy, and has fewer cardiovascular complications. For its acceptance as a valid alternative to CEA, CAS must fulfill the same criteria of safety, effectiveness and durability. patients receive a dual antiplatelet regimen consisting of aspirin (150mg daily) and clopidogrel (75mg daily). This treatment is started at least 5 days before the stenting. The procedure is performed under local anesthesia in an angiography suite with biplane digital subtraction and road-mapping |