الفهرس 
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Abstract
Summary
The aim of this study is to study and compare the effect of Ethinyl Estradiol versus sildenafil citrate on pregnancy rates in unexplained infertility females undergoing induction of ovulation by clomiphene citrate .
The study included 100 patients who were randomized into two groups. group 1 included 50 patients who were given clomiphene citrate 50 mg twice times per day orally and sildenafil citrate 20 mg of the same cycle three times per day orally and group 2 included 50 patients who were given clomiphene citrate 50 mg twice times per day orally and Ethinyl Estradiol tablets for 5 days .
Transvaginal u/s was done to detect endometrial thickness and number of follicles on day 13 or 14 of the cycle Finally , pregnancy was detected chemically by measuring B-HCG.
• Measuring percentage in change in primary outcome in both groups we found that percentage change in follicular number in both groups was statistically insignificant except for the 2ndcycle with ( p value 0.012) .
• Endometrial thickness in both groups was statistically significant between two groups in the 3 cycles with p- value (0.0l9) ( 0.001) (0.008) respectively.
• Increase pregnancy rate to be 56% with Estradiol versus 30% with Sildenafil. Pregnancy rate was statistically significant between both groups with pvalue 0.04l in the 3rd cycle.
It could be concluded from this study that oral use of sildenafil citrate 20 mg or Ethinyl estradiol in females undergoing induction of ovulation lead to increase number of follicles, endometrial thickness and so increase pregnancy rate but Ethinyl estradiol has better results. We recommend from this study to detect their effect of on pregnancy and fetal outcome in pregnant women.