الفهرس 
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Abstract
I am sincerely indebted and profoundly grateful to Prof. Dr.
Mohamed Mokhtar, Professor of Pharmaceutical Organic
Chemistry, Head of Pharmaceutical Organic Chemistry Department,
Faculty of Pharmacy, Suez Canal University, for suggesting the
research point, his valuable guidance, advices and scientific
supervision.
I would like to express my deep sense of gratitude to Assoc.
Prof. Dr. Hosam Eldin Abd El-hamed, Associate Professor of
Pharmaceutical Organic Chemistry, Faculty of Pharmacy, Suez
Canal University, for his helpful guidance, supervision and
encouragement during the development of this work.
I wish to express with thankfulness my deep sense of
gratitude to Dr. Yasmine Mohamad Abd El Aziz, Lecturer of
Organic Chemistry, Faculty of Pharmacy, Suez Canal University, for
constant encouragement, fruitful advices, writing help and priceless
support throughout the practical work.
I wish to express my thanks to Marwa Aly Elmetwaly Elewa
Lecturer of Pharmaceutical Organic Chemistry, Faculty of
Pharmacy, Suez Canal University for her priceless support during
writing this thesis, valuables advice and continuous support.
I wish to express my love and thanks to my parent, my sister
Ranwa and my brother Zeyad for continuous help and support.
I wish to express my love to my husband and daughters for
their love, support and encouragement to finish this work.
Finally, I am indeed grateful to everyone who made this work
to take its present form.