الفهرس 
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Abstract
This study was aimed to evaluate whether patients with IDA have renal injury which can be determined by urinary kidney injury marker Kidney injury molecule-1( KIM-1).
This study included:
1- 29 children suffering from iron deficiency anaemia as a study group.
2- 30 healthy children were taken as a control group, they were age and sex matched.
The cause of IDA was nutritional iron deficiency in our study group patients.
The control group was healthy patients without anemia, diseases affecting kidney function, or history of long-term drug use or any drug use during the last 2 months.
The study and control group included in our study were subjected to complete history taking, through clinical examination with stress on anthropometic measures and lay a concentration on sign of anemia .
They were also subjected to some laboratory investigations including complete blood count (CBC), S. Iron, S. Ferritin and TIBC (Total Iron Binding Capacity), renal function tests, urinary Kidney Injury Molecule 1 (Kim-1)
by ELISA Kit .
Our Study showed that higher urinary kidney injury molecules in iron deficiency patients (IDA) suggest a possible subclinical renal injury in pediatric IDA patients whose renal functions and serum electrolytes were normal.
Also showed that serum urea and creatinine of patients and control subjects were in the normal range, with no significant differences between IDA and control groups. On the other hand, there were significant negative correlations between hemoglobin, hematocrit, red blood cell count, and , KIM-1 levels
Our study suggests that patients with IDA may have renal injury determined by urinary kidney injury marker including KIM-1 Reduced oxygen delivery to kidneys and altered cell function due to anemic hypoxia may be key factors.
So we can conclude that urinary KIM-1 could be more sensitive marker for subclinical kidney damage in IDA patients and thus it could be a useful biomarker for detecting early kidney injury.