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العنوان
Biochemical Studies On The Effect Of Parsley Petroselinum Crispum In Experimentally Induced Diabetic Rats =
المؤلف
Sobhy, Hadir Mohamed Ahmed.
هيئة الاعداد
باحث / هدير محمد صبحي
مشرف / نبيل محمد طه
مشرف / عبد الوهاب على مندور
مناقش / السيدة السيد النويرى
مناقش / ماهر عبد النبي كامل
الموضوع
Biochemistry.
تاريخ النشر
2018.
عدد الصفحات
114 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
البيطري
الناشر
تاريخ الإجازة
26/6/2018
مكان الإجازة
جامعة الاسكندريه - كلية الطب البيطرى - الكيمياء الحيوية
الفهرس
Only 14 pages are availabe for public view

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from 107

Abstract

The study was performed in Faculty of veterinary medicine; Alexandria university Biochemical department to detect the biochemical effect of Petroselinum crispum on streptozotocin induced diabetic albino rats.
The study lasted for 30 days and was carried out on 40 albino rats of 150-180 gm body weight were divided into 4 groups (10 rats / group)
group 1: control group
This group contains 10 rats and kept on basal ration
group 2: Parsley group
This group contains 10 rats and kept on basal ration + Parsley 2gm/kg body weight
group 3: Diabetic group
This group contains 10 rats and kept on basal ration
group 4: Diabetic + Parsley
This group contains 10 rats and kept on basal ration + Parsley 2gm/kg body weight
Blood samples collected from each group and centrifuged to get the serum to perform the following biochemical analysis:
1. Fasting blood glucose
2. Glycosylated hemoglobin
3. Fructosamine
4. Fasting insulin and HOMA
5. Liver function
6. Kidney function
7. Lipid profiles
After collection of blood samples, animals slaughter to take liver washed with saline to determine the following parameters:
1. GSH
2. NO
3. MDA
4. Total antioxidant capacity
The results and statistical analysis revealed the following:
1. Treatment of the STZ induced diabetic rats with parsley resulted in significant decrease in fasting blood glucose and Hba1c compared to control group but there is no significant difference within all groups in fructose amine
2. Treatment of the STZ induced diabetic rats with parsley has no significant difference within all groups in liver and kidney function
3. Treatment of the STZ induced diabetic rats with parsley has no significant difference within all groups in lipid profile
4. Treatment of the STZ induced diabetic rats with parsley resulted in significant increase in liver antioxidants.