الفهرس 
Introduction
Chapter 1: Acute Kidney InjuryOnly 14 pages are availabe for public view
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Abstract
Acute kidney injury (AKI) is a clinical condition often seen in the neonatal intensive care unit (NICU). Until the third day of life, serum creatinine levels in neonates are a reflection of maternal serum creatinine levels. Thereafter, creatinine levels gradually DROP and within the next 2–3 weeks are normalized in 93 % of neonates (Jetton et al.,2012).
This study aimed to determine the incidence and outcome of AKI in preterm neonates admitted at EL MINIA university neonatal intensive care unit.
The medical records of prospective study of 100 pretrerm neonates admitted to El Minia neonatal intensive care unit of El Minia university hospital. During the period of 10 months from (February 2016 to December 2016) were investigated for AKI during threir incubation period.
Data collected include:
History include
Demographic data: (Sex, age on admission, gestational Age, weight)
Maternal history: Age of mother, consanguinity between parents and its degree.
Obstetric history: Parity, gravidity, place of delivery, mode of delivery, cause of C.S, number of living children, number of pregnancies, obstetric and medical problems, medical problems and treatment received, duration of PROM, prenatal steroid administration.
Natal history: especially evidence of perinatal hypoxia including: poor Apgar ,history of meconium, home delivery….etc
(2)Investigations done during admission:
Serum creatinine,
Blood urea nitrogen(BUN),
C reactive protein,
Complete blood count(CBC)
Blood culture.
Results
In our study ,of all patients with AKI, 64.5% developed stage(1) disease, 22.5% met the thresholds for stage 2, and 12.9% developed stage 3.In our study most of the patients had stage( 1) disease,which is in, concordance with the findings of Askenazi et al.,(2009).
In our study mortality due to AKI (stage 3 and 2 ) among very low
Birth weight (stage 3:100% and stage 2:85.7%), while in Stojanovie ., et al(2014) study very high mortality due to AKI (stages 3 and 2) among very low birth weight (VLBW) and extremely low birth weight (ELBW) neonates (stage 3: 83.3–100 % and stage 2: 66.6–100%)
In our study100%of neonates with AKI had BW<1,500 g, and 54.8%were born before the 28th week of gestation.
Our study revealed that the overall incidence of AKI in Premature infants admitted at EL MINIA university hospital was 31%and the mortality rate in the group of newborns with AKI was high (70.9%).