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العنوان
Instrumental Analysis of Certain Oral Hypoglycemic and Certain Chemotherapeutic Agents in the Pharmaceutical Formulations /
المؤلف
Amin, Mohammed Mahmoud Al Sayed.
هيئة الاعداد
باحث / Mohammed Mahmoud Al Sayed Amin
مشرف / Sobhy Mohamed El Adl
مشرف / Samia Mahmoud Mostafa
مشرف / Salah Abdel-Muttlib Abdel-Aziz
الموضوع
Pharmaceutical Chemistry. Pharmacy.
تاريخ النشر
2017.
عدد الصفحات
217 P. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الصيدلة ، علم السموم والصيدلانيات
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة قناة السويس - كلية الصيدلة - الكيمياء الصيدلية
الفهرس
Only 14 pages are availabe for public view

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from 217

Abstract

This thesis consists of six chapters;
Chapter 1: General introduction and literature review, which is divided into five parts: (A) - general introduction on oral hypoglycemic anti-diabetic drugs, (B) - general introduction on chemotherapeutics and anti-microbial agents, (C)- general introduction on redox reactions in pharmaceutical determination, (D) general introduction on HPLC importance and applications in pharmaceutical analysis and (E) literature review on the studied drugs.
Chapter 2: Development and application of bromometric method for estimation of Glibenclamde, Gliclazide, Glimepiride and Pioglitazone hydrochloride in bulk and tablet formulations.
Chapter 3: Spectrophotometric determination of Glibenclamide and Glimepiride using 4-chloro-7-nitrobenzo-2-oxa-1,3-diazole(NBD-Cl) in bulk and tablets.
Chapter 4: Optimization and validation of HPLC method for simultaneous estimation of Vildagliptin, Pioglitazone hydrochloride and Glimepiride in bulk and tablets.
Chapter 5: Validated isocratic HPLC method for simultaneous estimation of Metronidazole, Tinidazole and Ciprofloxacin hydrochloride in bulk and tablets. Chapter 6: Validated stability study of Metronidazole, Tinidazole and Ciprofloxacin hydrochloride in bulk and tablets using a gradient HPLC method.