الفهرس 
Embryology of tympanic membrane
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Abstract
Summary
Myringoplasty is the definite treatment of tympanic
membrane perforation. Our aim is complete closure with satisfactory
hearing results.
In our study we compared two groups each one is 25 patients
with medium sized tympanic membrane perforation. In group “I”,
we used platelet rich plasma enriched fat graft in myringoplasty and
in group “II”, we used the classical cartilage perichondrium one.
For the graft take rate, 22 (88%) patients had a successful
outcome in the PRP enriched fat graft myringoplasty group and 23
(92 %) patients had a successful outcome in the classical cartilage
perichondrium myringoplasty group.
Regarding the postoperative hearing improvement, there was
a significant improvement in both groups, in PRP enriched fat graft
myringoplasty group “I”, the mean air bone gap was (20.76 ± 4.62)
preoperatively and it was (6.64 ± 2.41) postoperatively.
While in classical cartilage perichondrium myringoplasty
group “II” the mean preoperative (A.B.G) was (22.76 ± 4.94) and
postoperatively was (7.12 ± 2.71).
These results showed significant postoperative hearing
improvement, while there was no significant difference in the
postoperative (A.B.G) between both groups.Finally, the PRP enriched fat graft myringoplasty is a
minimally invasive, effective procedure in management of the
medium sized tympanic membrane perforation. Also it is safe and
feasible procedure, with good success rates for tympanic perforation
closure and recovery of hearing thresholds and there was no
significant difference in results between it and the classical cartilage
perichondrium myringoplasty.Conclusion
The PRP enriched fat graft myringoplasty is a minimally
invasive, effective procedure in management of the medium sized
tympanic membrane perforation. Also it is safe and feasible
procedure, with good success rates for tympanic perforation closure
and recovery of hearing thresholds and there was no significant
difference in results between it and the classical cartilage
perichondrium myringoplasty.