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العنوان
The Effect of Curcumin as a Toll-Like Receptor
4 Antagonist on the Course of Experimental
Trichinellosis /
المؤلف
El-Guindy, Dina Ahmed Samy Mohamed.
هيئة الاعداد
باحث / دينا احمد سامى محمد الجندى
مشرف / ابراهيم عبد الفتاح ابو الاسعاد
مشرف / مها مصطفى شملولة
مشرف / داليا صلاح عاشور
الموضوع
Parasitology.
تاريخ النشر
2017.
عدد الصفحات
p 186. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
الطب (متفرقات)
تاريخ الإجازة
19/4/2018
مكان الإجازة
جامعة طنطا - كلية الطب - Parasitology
الفهرس
Only 14 pages are availabe for public view

from 231

from 231

Abstract

SUMMARY AND CONCLUSIONS
Trichinellosis is a huge food-borne parasitic zoonotic disease
caused by eating undercooked or raw meat harboring the infective
Trichinella larvae. It infects many mammalian, avian and reptile
host species in which the adult worms and the larvae reside in the
small intestinal and muscle tissues, respectively. Human
trichinellosis has been documented in 55 countries in the world.
Trichinellosis is an emerging and re-emerging zoonotic disease with
health, economic and social impacts in developing countries. The
clinical diagnosis of trichinellosis is hard as the clinical symptoms
are nonspecific.
Trichinella infection in the human host can be divided into
two phases: an intestinal (or enteral) phase and a muscular (or
parenteral) phase. Infections with low intensities can remain
asymptomatic, but infection with more than a few hundred larvae
results in gastroenteritis in the form of abdominal pain and diarrhea
about 2 days P.I. (intestinal acute phase of disease). Migrating
Trichinella larvae and their metabolites provoke an immediate
reaction, resulting in pathological, immunological and metabolic
disturbances and the various clinical phenomena observed during the
acute stage of the infection. The immunological reaction is
characterized by infiltrating inflammatory cells (i.e., mast cells,
eosinophils, monocytes and lymphocytes).
The severity of clinical disease in T. spiralis depends on the
number of infective larvae ingested by the patient. Thus, infection
may result in various clinical forms ranging from asymptomatic to.