الفهرس 
IntroductionOnly 14 pages are availabe for public view
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Abstract
Our results demonstrated that: The corneal endothelial cell layer in high myopic eyes tends to have less endothelial cell density and cell hexagonality compared to emmetropic eyes. Nevertheless, there is no significant difference in CV between emmetropic and high myopic eyes.
The progression of myopia leads to elongation of the eye ball. As a result, the more myopic eye tends to have more enlargement of the globe. So, as long as the eye elongate, the corneal endothelial surface area increases. Due to little or no mitotic activity of the corneal endothelial cells after birth, it is likely that the corneal endothelial cells have to floor the enlarged surface. Then, reduced corneal endothelial density is expected. Since corneal endothelial cells have to flatten to conquer the enlarged surface, it is conceivable that the possibility of polymorphism increases. Subsequently, the percentage of hexagonal appearance of the cells decreases.
from the previous studies, we knew that factors that affect the corneal endothelial cell density and morphology are corneal disease, glaucoma, pseudoexfoliation, history of trauma, Diabetes Mellitus, age, race, ocular surgeries (cataract, refractive), years of contact lens wear. from our study, we added high myopia as a factor that affect the corneal endothelial cell density & morphology.
We strongly recommend that any subject with high myopia that will undergo cataract operation, refractive surgery or contact lens wear for a long time to do a specular microscopy imaging of the endothelial cells prior the procedure to avoid the risk of corneal decompensation.