الفهرس 
INTRODUCTIONOnly 14 pages are availabe for public view
 |  | from | 122 |  |  |
| | | from | 122 | | |
Abstract
Narrow band imaging (NBI) depicts distinct intramucosal vascular network and pit pattern without any use of dye technique. It is thus suggested that NBI can be used for the assessment of severity in inflammatory bowel diseases, especially in UC.
In the active UC, NBI colonoscopy depicts friability as a black area. In the inflamed granular mucosa, crypt openings and villous structure become evident through the procedure. In the inactive UC, there are two types of mucosal vascular pattern; one being composed of deep, green vessels and superficial, black vessels, and the other lacking in superficial vessels.
With used of a magnifying instrument, the active mucosa can be classified into the mucosa with obvious crypt openings and that with villous structure. Mucosal vascular pattern in the inactive mucosa is shown as a honeycomb-like structure or irregular, tortuous structure under magnifying NBI observation.
Furthermore, such NBI findings show close correlations with histologic findings including crypt distortion, goblet cell depletion and basal plasmacytosis. Therefore, NBIcolonoscopy might be of value for the precise assessment of histologic severity in active and inactive UC.
Our study was conducted to assess degree of concordance between NBI (Narrow band imaging), histopathology and Computed tomography scan in diagnosis of Ulcerative Colitis.
This study will include 50 patients who will present to Gastroenterology unit, Alexandria Main University, Faculty of Medicine, with suspected ulcerative colitis.
Laboratory tests were done to all patients including CBC, CRP, ESR, Fecal calprotectin also CTC (CT Colonography ) and NBI colonoscopy and biopsies were collected from all patients for histopathological assessment done to all of them and data collected and interpretation done.
Results:
1. The majority of patients with UC are in the age group of 30-40 years at diagnosis.
2. Any age group from infants to the elderly can be affected, but the peak age of onset is between 15 and 30 years with a second but smaller peak between 50 and 70 years.
3. Most UC studies have shown a male predominance or an equal distribution between genders .
4. According to the Montreal classification, based on location, UC can be classified into three different subtypes: proctitisE1 (when inflammation is restricted to the mucosa of the rectum), left colitis E2(when inflammation extends beyond the rectum and to the splenic flexure) and extensive colitisE3 (when inflammation reaches the mucosa proximal to the splenic flexure. E2>E1>E3
5. Disease activity decrease with