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العنوان
Effect of Dexamethasone on Daily Fetal Movement, Umbilical and Middle Cerebral Arteries Doppler and Cardiotocogram /
المؤلف
Ibrahim, Nader Mohamed.
هيئة الاعداد
باحث / Sherif Abd El-khalek Akl
مشرف / Sherif Hanafi Hussain
مشرف / Ahmed Ali Alanwar
مناقش / Ahmed Ali Alanwar
تاريخ النشر
2018.
عدد الصفحات
163p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
طب الأطفال ، الفترة المحيطة بالولادة وصحة الطفل
تاريخ الإجازة
1/1/2018
مكان الإجازة
جامعة عين شمس - كلية الطب - النسا والتوليد
الفهرس
Only 14 pages are availabe for public view

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from 163

Abstract

SUMMARYUMMARY UMMARY
rematurity complications have been a timeless problem and a cause of death among live born infants, especially the problems concerning lung maturity and pulmonary surfactant formation.
Steroids’ use has been acknowledged as a way to prevent many of the complications, such as intraventricular haemorrhage, and the pulmonary complications, such as respiratory distress syndrome.
The use of steroids, namely Dexamethasone, has been speculated to cause some clinical side effects, along with some physiological alterations, and several studies have been conducted to detect them. Some of these effects are the influence of steroids on Doppler arterial velocity waveforms, biophysical profile, daily foetal movement count, and cardiotocography.
In our study, we selected 110 women with no foetal risk, with gestational age at term, and gave them a single course of Dexamethasone, consisting of 4 doses of 6 mg.
All women were subjected to the following before the administration, and 24 to 48 hours after the last dose, specifically between the 60th and the 72nd hours:
 Doppler waveform velocities of the UA and the MCA represented by the PI and RI.
 20 minutes cardiotocography nonstress test trace.
P
Summary 
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Women were instructed to count the foetal movements with the Sadvosky method since the first day, and for 5 days.
Paired T tests were done to compare results before and after administration, except short term variability for which the McNemar’s non-parametric test was used. Pearson’s correlation coefficient was used as a correlation test.
We had the following outcome:
 Decrease in MCA PI.
 Decrease in foetal movement count on the second day.
 Increase in short term variability.
 Direct correlation between the short term variability and gestational age (coincidal finding).
 Direct correlation between the MCA RI and the UA PI with the foetal movement decrease on the 5th day.