الفهرس 
Leptin nature and physiologyOnly 14 pages are availabe for public view
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Abstract
Leptin is a 16 kilodalton protein that is encoded by the
ob gene and secreted by adipocytes. The main target receptors are present in the hypothalamus where leptin exerts
its action causing anorexia, stimulating thermogenesis and
increasing metabolism. Recently an increased circulatory
level of leptin was reported in women with alcoholic
cirrhosis. We studied the serum leptin in cirrhosis and normal healthy control and its possible correlation with the
nutritional status, liver function, and the type of viral
hepatitis.
The study included 30 patients with different stages of
liver cirrhosis and 10 normal healthy controls. Diabetic
patients and patients with intercurrent infections are
excluded.
We concluded the association of liver cirrhosis and
increased serum leptin also the relation between increased serum leptin and the severity. of liver cirrhosis.