الفهرس 
Introduction to lymphomaOnly 14 pages are availabe for public view
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Abstract
Background: Lymphoma is a group of blood cell tumors that develop from lymphocytes (a type of white blood cell). The name often refers to just the cancerous ones rather than all such tumors. Aim of the Work: to measure level of sPD-L1 in patients with DLBCL at baseline with correlation with patients’ outcome. Patients and Methods: The study included thirty adult patients at hematology/ oncology and bone marrow transplantation Department, Ain Shams University in Cairo, Egypt, International medical center (IMC) and Al-Maadi military hospital. They were recruited from inpatients and outpatients departments with age above 16 years old newly diagnosed with Diffuse large B cell lymphoma during the years 2016 and 2017.Results: The present study showed highly statistically significant difference between patients before and after treatment according to SPDL-1.Conclusions: sPDL-1 is elevated in DLBCL at diagnosis which indicates a role of PDL-1 in the immune escape mechanism of lymphoma cells. Recommendations: 1- Large studies with longer duration are required to confirm our results and to assess the impact of sPDL-1 on OS and PFS in the DLBCL patients.