الفهرس 
Recurrent pregnancy lossOnly 14 pages are availabe for public view
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Abstract
Recurrent pregnancy loss refers to the consecutive loss of three or more clinically recognized pregnancies prior to the 20th week of gestation (excluding ectopic, molar and biochemical pregnancies)(Marguard K at al., 2010).Known causes or associations of recurrent miscarriage are endocrine,immunological, anatomical and genetic, although about 50 % of cases are classified as idiopathic. In recent years attention has been drawn to the possible association of both early and late pregnancy loss with either acquired or inherited thrombophilic defects predisposing to the development of deep vein thrombosis(Sandra M, 2014) (Aysha Ali at al., 2016).Hemostasis is a complex process in which multiple components of the blood clotting system are activated in response to vessel injury to control bleeding,Hemostasis is composed of four major events, Primary hemostasis,Secondary hemostasis, Fibrin clot formation and stabilization and Inhibition of coagulation (Luchtman-Jones L and Broze GJ, 1995).Thrombophilias are hereditary or acquired abnormalities which can increase the risk of venous or arterial thrombosis (Lijfering WM at al.,2010).Several studies have demonstrated an association between the presence of a thrombophilic disorder and adverse obstetric complications such as Severe pre-eclampsia, abruptio placentae, intra uterine growth retardation (IUGR) , stillbirth and recurrent miscarriage contribute greatly to maternal & fetal morbidity and mortality.