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العنوان
Incidence of Fungi and Mycotoxins Incriminated For Human Aspergillosis /
المؤلف
Ahmed, Enas Mahmoud Amer.
هيئة الاعداد
باحث / إيناس محمود عامر أحمد
مشرف / محمد فوزي آدم
مناقش / هاني مباشر
مناقش / ناجح أبو دهب
الموضوع
Fungi.
تاريخ النشر
2018.
عدد الصفحات
125 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
علوم النبات
الناشر
تاريخ الإجازة
27/2/2018
مكان الإجازة
جامعة أسيوط - كلية العلوم - Botany and Microbiology
الفهرس
Only 14 pages are availabe for public view

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Abstract

In this investigation full history was taken from 250 patients with respiratory diseases who admitted chest department and respiratory intensive care unit at Assiut University Hospitals using pre-designed questionnaire sheet according to legal regulations and local ethics committee requirements and screened for aspergillosis disease with conventional methods and new technique ”exhalation air fungal culture”. Then the potentiality of eighty fungal isolates belonged to four species Aspergillus flavus (20 isolates), A. fumigatus (15 isolates), A. niger (30 isolates) and A. terreus (15 isolates) isolated in this study were tested for their enzyme properties as well as mycotoxins. Finally the antifungal activity of four types of active compounds (amphotericin B, fluconazole, itraconazole and micafungin) were tested on 40 selected isolates belonging to four fungal species (Aspergillus flavus, A. fumigatus, A. niger and A. terreus, ten of each).
The main results that were obtained can be summarized as follow:
1-The conventional methods revealed the presence of four species of Aspergillus which were A. niger, A. fumigatus, A. flavus and A. terreus.
2- Aspergillus niger was the most dominant species with 32% of the total isolates followed by A. fumigatus and A. flavus with almost the same percentage (29%) and finally A. terreus came with the least appearance among isolates (10%).