الفهرس 
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Abstract
1,2,4-Triazole represents an important class of heterocyclic unit found
to have wide range of applications in chemistry and biology.83
Particularly, heterocycle fused-triazoles received a long standing interest
due to their medicinal relevance. [1,2,4]Triazolo[4,3-a]pyridine, a hybrid
1,2,4-triazole and pyridine, is an important prototype of this family, and
one of the well studied systems of this kind in literature. This motif
embedded compounds are found to display biological activities such as
antibacterial, antifungal, anti-inflammatory, antiproliferative,
antithrombotic, anticonvulsant, herbicidal, and anxiolytic activity. Like
triazolopyridines, triazolopyridazines, and the diazine congeners,
triazolopyrimidines as well as triazoloquinolines are other important
frameworks that belong to heterocycle fused-triazoles wherein 1,2,4-
triazole is fused with pyridazines, pyrimidines, and quinolines,
respectively. Owing to their broad spectrum of biological activities,
heterocycle fused-triazoles have gained considerable interest among the
researchers and these systems can be routinely synthesized by
constructing the 1,2,4-triazole motif by adopting either dehydrative
cyclization of acyl hydrazides or oxidative cyclization of heteroaryl
hydrazones. Although the former method was used successfully for the
efficient preparation of numerous heterocyclic compounds, the latter is
the most common, attractive and widely exploited method.