الفهرس 
Gross AnatomyOnly 14 pages are availabe for public view
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Abstract
Pancreatic cancer is one of the most fatal cancers. Stage of the disease
greatly affects the prognosis of the disease that makes early diagnosis crucial
in the management of pancreatic cancers.
Conventional MRI with contrast enhancement is the routine MRI
protocol, however contrast administration is invasive and time consuming in
addition to the adverse effects of contrast. Also many cancer patients have
already impaired renal functions.
With development of high field magnets and great advances in
functional MRI, DWI is increasingly used as in the detection and
characterization of abdominal tumors.
DW MRI in the pancreas is a new imaging technique. It has the
advantage that it can be obtained without breath-holding, using respiratory
triggered technique. It is simple and non-invasive with no need to use
contrast media and it provides information that reflects tissue cellularity
which can be used in assessment of pancreatic lesions.
In our study using combined qualitative analysis of DWIs and
quantitative analysis of ADC values we concluded that results of DW MRI
are approaching that of contrast enhanced MRI not only in detecting
pancreatic neoplasms but also in detection of vascular encasement, tumor
necrosis and liver metastasis which are essential information for the clinician
that reflects disease prognosis and treatment strategies. However, in view of
limited number of cases and other limitations of the study larger studies are
needed to confirm these results.