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Abstract This prospective study aimed to asses the efficacy and safety of ketogenic diet and modified atkin diet in controlling cases of intractable epilepsy from one month to 3 years in comparison to children treated by antiepileptic drugs only in pediatric neurology clinics. With mean age of 3.15±2.92 years. 15 patients starting modified atkins diet. They were recruited from Pediatric Neurology and Nutrition outpatient Clinics, Children Hospital Ain Shams University hospital,and Benha children hospital during the period from Decemder 2015to December 2016. All subjects underwent full history taking, clinical examination and laboratory investigation, including CBC, urinary acetone ,serum lipid profile (cholesterol, triglycerides, LDL, HDL) before and after 3months of ketogenic diet therapy Regular outpatient visits were done at monthly intervals for a period of 9 months, during which, any reduction in seizure frequency or severity was recorded. The patient’s toleration to the diet was recorded, and any complication was treated accordingly. |