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Abstract Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and the prognosis of patients with untreated hepatocellular carcinoma is poor. Surgery is actually considered the treatment of choice but few patients are candidates at the time of diagnosis. Thus, several nonsurgical techniques such as transarterial chemoembolization (TACE) & radiofrequency ablation (RFA) have been introduced for treatment of HCC. Treatment monitoring after local-regional therapy for HCC is sometimes challenging because tumor necrosis may not always be paralleled by a reduction in tumor size. Therefore, CT perfusion can be a promising technique to monitor treatment response for local-regional therapies since it allows quantification of hemodynamic changes within the tumor. The aim of this study is to evaluate the diagnostic role of the quantitative assessment of multidetector computed tomographic perfusion imaging in evaluation of therapeutic response of transarterial chemoembolization and radiofrequency ablation for hepatocellular carcinoma. We enrolled in this study patients ( males and females) mean age was years, range - years. All patients had HCC treated by either transarterial chemoembolization (TACE) (n= ) versus radiofrequency ablation (RFA) (n= ). All patients were evaluated by careful history taking, clinically evaluated, and then subjected for radiological examination included triphasic study of the liver and CT perfusion study. By triphasic CT, out of patients treated by either TACE versus RFA, patients ( TACE treated & RFA treated) ( ) ( ) were |