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العنوان
Role of computed tomography perfusion in evaluation of the therapeutic response of transarterial chemoembolization and radiofrequency ablation for hepatocellular carcinoma /
المؤلف
Salem, Logain Nabil Mohammed.
هيئة الاعداد
باحث / لجين نبيل محمد سالم
مشرف / محمد حسن الشافعي
مناقش / دينا مغازي محمد
مناقش / دينا حازم زيادة
الموضوع
Radiodiag. Radiodiagnosis and medical imaging.
تاريخ النشر
2017.
عدد الصفحات
232 p. :
اللغة
الإنجليزية
الدرجة
الدكتوراه
التخصص
الأشعة والطب النووي والتصوير
تاريخ الإجازة
21/2/2018
مكان الإجازة
جامعة طنطا - كلية الطب - Radiodiagnosis and medical imaging
الفهرس
Only 14 pages are availabe for public view

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from 275

Abstract

Hepatocellular carcinoma (HCC) is one of the most common cancers
worldwide and the prognosis of patients with untreated hepatocellular
carcinoma is poor. Surgery is actually considered the treatment of choice but
few patients are candidates at the time of diagnosis. Thus, several nonsurgical
techniques such as transarterial chemoembolization (TACE) &
radiofrequency ablation (RFA) have been introduced for treatment of HCC.
Treatment monitoring after local-regional therapy for HCC is
sometimes challenging because tumor necrosis may not always be paralleled
by a reduction in tumor size. Therefore, CT perfusion can be a promising
technique to monitor treatment response for local-regional therapies since it
allows quantification of hemodynamic changes within the tumor.
The aim of this study is to evaluate the diagnostic role of the
quantitative assessment of multidetector computed tomographic perfusion
imaging in evaluation of therapeutic response of transarterial chemoembolization
and radiofrequency ablation for hepatocellular carcinoma.
We enrolled in this study patients ( males and females) mean
age was years, range - years. All patients had HCC treated by either
transarterial chemoembolization (TACE) (n= ) versus radiofrequency
ablation (RFA) (n= ).
All patients were evaluated by careful history taking, clinically
evaluated, and then subjected for radiological examination included triphasic
study of the liver and CT perfusion study.
By triphasic CT, out of patients treated by either TACE versus
RFA, patients ( TACE treated & RFA treated) ( ) ( ) were