الفهرس 
Fine needle aspiration technique and breast diagnostic
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Abstract
Accurate interpretation of various breast lesions requires a close working relationship between the clinician, the radiologist and the pathologist what is called triple test assessment. The pathologist in this test mostly works through interpretation of FNAC (fine needle aspiration cytology) and/or core biopsy as a trial to minimize the proportion of excision biopsies for diagnostic purposes especially for benign lesions.
Aim: Evaluate the diagnostic accuracy of FNAC using different special stains in different breast lesions through comparing its results with the definite biopsy results and find out the common diagnostic pitfalls as well as evaluate the role of triple test assessment in improving the diagnostic accuracy of FNAC.
Material and Methods: This study was carried out on 77 cases of different breast lesions who underwent FNAC and biopsies interpretations at Ain shams university hospitals pathology units from 2014 till 2017 with their clinical and radiological assessments. Correlation between FNAC and biopsy results and the clinical and radiological assessment was done.
Results: Mucious carcinoma was found to be a diagnostic pitfall with benign breast lesion on cytological examination but radiologically it was suspicious. Thus, the diagnostic indices of FNAC were as follow: sensitivity of 96.6%, specificity of 100%, and diagnostic accuracy of 98.7% , and all diagnostic indices reached 100% when FNAC incorporated in triple test assessment.
Conclusion: Mucinous carcinoma is an important diagnostic pitfall with benign breast lesions in cytology but if the clinical and radiological correlations are taken critically in consideration, further investigation by biopsy for better evaluation of the lesion will be done and misdiagnosis will be avoided. Thus, diagnostic indices for FNAC can improved from 96.6%.for sensitivity and 100%for specificity.
Abbreviations: FNAC (fine needle aspiration cytology), CNB (core needle biopsy), BIRADS (Breast Imaging Reporting and Database System), FCCs (fibrocystic changes), UDH(usual ductal hyperplasia), ADH(atypical ductal hyperplasia), DCI(duct carcinoma in situ)