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العنوان
24-Hour Blood pressure variability in Normotensive women with history of preeclampsia / eclampsia /
المؤلف
Saied, christina Eid.
هيئة الاعداد
باحث / كرستينا عيد سعيد بطرس
مشرف / محمد عبدالقادر عبدالوهاب
مشرف / حازم محمد علي
الموضوع
Blood Pressure Monitoring, Ambulatory. Blood Pressure - Physiology. Blood Pressure Determination.
تاريخ النشر
2017.
عدد الصفحات
94 p. :
اللغة
الإنجليزية
الدرجة
ماجستير
التخصص
أمراض القلب والطب القلب والأوعية الدموية
تاريخ الإجازة
1/1/2017
مكان الإجازة
جامعة المنيا - كلية الطب - أمراض القلب والأوعية الدموية
الفهرس
Only 14 pages are availabe for public view

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Abstract

• Preeclampsia is characterized by de-novo hypertension and proteinuria, sometimes progressing to affect various organs such as the central nervous system, lungs, liver, kidneys, coagulation, and the cardiovascular due to excessive inflammation and endothelial damage, and these changes may persist after the end of pregnancy complicated with such syndrome.
• Blood pressure variability up and down between day time and night time, between seasons in the same year, between years in our lives and even between every heart beat is a very important factor that can affect heart itself and all other body organs.
• The main aims of this study is:
• To determine different blood pressure variability indices in women with past history of Preeclampsia / Eclampsia using 24-hour ambulatory BP monitoring.
• To determine any form of persistent cardiovascular or renal implication following a pregnancy complicated with preeclampsia/Eclampsia.
• To determine the correlation between different ABPM variability indices and these implication and to determine the significance of such correlation.
• The current study was conducted at Minia university hospital- Hypertension clinic during period from April 2016 to May 2017. This study included 101 formerly normotensive women who experienced a pregnancy complicated with preeclampsia/eclampsia matched with 42 women with normotensive pregnancies.
• All women in this study were subjected to
• History taking and clinical examination including office BP measurement and measurement of weight and height to calculate body surface area and body mass index.
• 24 hours Ambulatory blood pressure monitoring (ABPM) to calculate blood pressure variability indices.
• Echocardiography to assess Left Ventricular Ejection Fraction (LVEF), Left Ventricular Mass Index (LVMI), diastolic function, Ascending aortic diameters to estimate aortic elastic properties.
• Laboratory investigations e.g. fasting blood sugar and serum creatinine and morning urinary samples for A/C ratio estimation.