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Abstract The aim of this study is to evaluate the role of diffusion- weighted magnetic resonance imaging in the detection and characterization of focal liver lesions aiming to be used as standard modality ( free ionizing radiation and free contrast media ) in detection and follow up of patients with hepatic focal lesion . For this purpose thirty patients with different hepatic focal lesions underwent diffusion-weighted MRI in addition to routine MRI (T1-T2) using 1.5-T whole body Philips machine and a body phased array coil. DW MRI was carried on using b values of 0,400 and 800 s/mm^2. They were 20 (66.7 %) males and 10 (33.3 %) females with mean age 51.5 ± 6.2 years with a range of 37-65 years. The malignant tumors were 25(83.3%) (5 metastases, 20 HCCs) and benign lesions were 5 (16.7%) (5 haemangiomas) obtaining 95% sensitivity and100 % specificity for diagnosing malignancy. |