الفهرس 
Aim of the WorkOnly 14 pages are availabe for public view
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Abstract
B
ecause of the time, high drug coasts, and emotional expenditure incurred by patients undergoing in vitro fertilization, identifying factors for fertilization in IVF therapy is extremely important. In the same context, the ideal marker for ovarian reserve is one that can be performed in basal state with high sensitivity and specificity for identifying patients who will have live pregnancy outcomes. There for the concept of diminished ovarian reserve has gained general acceptance in infertility medicine.
Many of ovarian tests have become part of routine diagnostic procedure for infertility patients who undergo assisted reproductive techniques the unifing goals are traditionally to find out the respond to stimulation and chance of pregnancy.
Evaluation of ovarian reserve has become an essential part of the treatment assessment of woman about to undergo assisted reproductive technique.
This has been most commonly achieved through recognition of woman age and level of her serum E2 level during the early follicular phase of the menstrual cycle.
The current observational analytical prospective study was carried out at the gynecology clinic and assisted reproductive technology unit of Ain Shams University maternity hospital included 50 women they were in the childbearing period with age range (18-49 ) years the patients who were excluded included who at extremes of age , women under hormonal treatment ,ovulation induction and drug affecting hormonal levels.
A special sheet was designed to this study, it was including patient name, age ,history of cycle irregularity, history of PCO, parity and history of infertility.
Serum samples were obtained on cycle days (3,5,10,21) of menestural cycle for each woman and were analyzed at the faculty of medicine ,research unit Ain Shams University
The results were tabulated and statistically analyzed by suitable statistical methods after completion of the study. The results were tabulated, the ratio or the correlation between (E2/FSH) was calculated on cycle days (3,5,10,21).
The final conclusions of results of this study shows that there negative correlation between basal (day2)(E2/FSH) which is equivalent or similar to that ratio on days(5,10,21) so there is no need to wait for hormonal analysis to the next cycle (day 2 ,or 3) to save time specially in patients >35years for them there is importance of cycle day3 for evaluation of ovarian reserve and prior ovulation induction and subsequent pregnancy potential during the infertility work up
Rigid adherence to cycle day 3 collection no longer seems necessary, as recommended in (Hansen et al., 1996) study that showed FSH values are equivalent on cycle days (2-5) and Estradiol begins to rise on cycle day 4 so negative correlation between Estradiol and FSH values only on cycle day 5.
These findings will add greater flexibility for both physicians and patients in evaluation of the infertile couple.