الفهرس 
Preterm LabourOnly 14 pages are availabe for public view
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Abstract
Objective: To estimate best cut-off values for mean fetal lung volume (FLV) and pulmonary artery resistance index (PA-RI) as a noninvasive measure to predict neonatal respiratory distress syndrome (RDS) in preterm fetuses.
Methods: A prospective study done at Ain Shams University Maternity Hospital, Egypt from May 2015 to July 2017, eighty eligible women presented with preterm labor were recruited at 32 – 36 weeks’ gestation. Before delivery Three-dimensional ultrasound was used to estimate FLV using virtual organ computer-aided analysis (VOCAL) and PA-RI was measured by Doppler ultrasonography.
Results: A total of 80 women were included. 37 (46%) of the newborns developed neonatal RDS. FLV was significantly lower in neonates who developed RDS (P = 0.04) whereas PARI was significantly higher in those who didn’t (P=0.02). A cut-off value for FLV ≤ 27.2 cm3 and PARI ≥ 0.77 predicted the subsequent development of RDS. Combining both cut-offs together yielded a more sensitive and specific method for prediction of RDS (sensitivity 100%, specificity 88.5%).
Conclusion: Measurement of FLV or PA-RI can predict RDS in the preterm fetuses. Combined use of both measures increased their predictive value.