الفهرس 
IntroductionOnly 14 pages are availabe for public view
 |  | from | 162 |  |  |
| | | from | 162 | | |
Abstract
Liver is one of the most vital organ, it has a prominent role in the regulation of physiological processes. It involved in varieties of vital function such as metabolism of nutrient as lipids, carbohydrates and vitamins. Furthermore, detoxification, metabolism and excretions of drugs and other xenobiotic from the body by detoxifying and eliminating them, also it regulate the level of plasma glucose, ammonia and cholesterol and other functions.
Liver diseases are among the most serious health problems.
Liver diseases are mainly caused by toxic chemicals (certain antibiotic, paracetamol, carbon tetrachloride, aflatoxins, peroxidized oil … etc), excess consumption of alcohol, autoimmune disorder and infection.
Up till now, orthotropic liver transplantation is the best effective treatment of liver diseases.
However, due to the shortage of donors, high costs, the number of patients who can benefit from this modality is very limited.
In recent years, cell based therapies have investigated as alternative to whole liver transplantation.
Thus the aim of this study was to investigate the effect of injection of bone marrow mesenchymal stem cells (BM-MSCs) on the experimental liver injury with acetaminophen.