![]() | Only 14 pages are availabe for public view |
Abstract Coumarins and their derivatives establish a family of compounds that possessing a wide spectrum of biological activity. Many of these compounds have proven to be active as antibacterial,antifungal, antiinflammatory anticoagulant, anti-HIV and antitumor agents. Coumarins are widely used as additives in food, perfumes, cosmetics, pharmaceuticals and optical brighteners and would dispersed fluorescent and laser dyes. Coumarins also have the super thermal stability and outstanding optical properties including extended spectral response, high quantum yields and superior photo stability. Optical applications of these compounds, such as laser dyes, nonlinear optical chromophores, fluorescent whiteners, fluorescent probes, polymer science, optical recording and solar energy collectors have been widely investigated.Classical routes of synthesis to coumarins incorporate Pechmann,Knoevenagel, Perkin, Reformatsky, and Wittig condensation reactions |